12 Further iterations and expansions of this grading scale, adapted from the coronary circulation scoring system (TIMI) and applied to quantify cerebral reperfusion, consistently demonstrated incremental correlation between functional independence and higher volume of distal antegrade contrast flow on angiography. 8–11 Given the significant heterogeneity among these scales, an expert panel established TICI scoring as an optimal angiographic assessment of cerebral reperfusion therapies with successful recanalization defined as perfusion with >50% distal branch filling (TICI 2b). Since the inception of the first thrombectomy trials, various angiographic grading scales have been used for evaluation of the degree of ischemic tissue reperfusion, including arterial occlusive lesion (AOL), thrombolysis of myocardial ischemia (TIMI), and thrombolysis of cerebral ischemia (TICI). 1–7 The success of EVT relies on rapid and efficient reperfusion of the salvageable ischemic brain tissue after revascularization of the occluded vessel. 6 Neurology, Marcus Stroke & Neuroscience Center Grady Memorial Hospital, Emory University School of Medicine, Atlanta, Georgia, USAĭr Radoslav Raychev, Neurology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, CA 90095, USA Įndovascular therapy (EVT) has emerged as a widely adopted and clinically proven treatment of acute ischemic stroke (AIS) due to anterior circulation large vessel occlusion (LVO) circulation.5 Neurosurgery, University of California Los Angeles, Los Angeles, California, USA.
4 Radiological Scieneces, University of Califronia Los Angeles David Geffen School of Medicine, Los Angeles, California, USA.3 BRIGHT Research Partners, Minneapolis, Minnesota, USA.2 Radiological Sciences, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, USA.1 Neurology, University of California Los Angeles David Geffen School of Medicine, Los Angeles, California, USA.
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